SuppCo’s
Essential Health for Women in their 40s
Protocol overview
Last updated: Feb 22, 2024
7 Nutrients
Magnesium Glycinate
300mg
Magnesium Glycinate is critical for numerous biochemical reactions in the body, supports muscle and nerve function, and can help manage stress levels. [1]
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Log in or sign upOmega-3 fatty acids
1000mg
Omega-3 Fatty Acids are essential for heart health, cognitive maintenance, and supporting a healthy inflammatory response. Choose a product containing a combined 500mg of EPA/DHA per serving. [2]
Iron
18mg
Iron supports energy metabolism and is important for women still experiencing menstruation. [3]
Folic Acid
400mcg DFE
Folic acid supports reproductive health and is crucial for DNA synthesis and repair. (For a precise explanation of why folic acid is recommended instead of methylated folate, and additional information relating to the MTHFR gene, please review the Warning section later in the Protocol). [4]
Vitamin D3
50mcg
Vitamin D3 plays an essential role in bone health, immune function, and may have a positive effect on mood. [5]
Probiotics
1billion CFU
Probiotics aid in promoting a healthy gut microbiome, which is essential for overall health, nutrient absorption, and immune function. Product strengths vary so look for those with at least 1 billion CFUs and multiple strains per serving. [6]
Vitamin B Complex
1 serving
Vitamin B-Complex is a collection of essential vitamins that support energy production, healthy skin and hair, and a balanced nervous system. [7]
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Warnings
Do Not Take With: High doses of other supplements, especially those containing iron or vitamin D, without consulting a healthcare provider to avoid potential excess.
Do Not Take If: You are pregnant, breastfeeding, or have a health condition, especially related to iron metabolism or hormonal balance, without first consulting a healthcare provider.
Folic Acid and Folate: Though fertility naturally declines with age, women in their 40s may still become pregnant. While many prenatal vitamins now contain methylated folate, only folic acid has been proven in large-scale clinical trials to prevent neural tube defects (NTDs), which is why it remains the standard of care recommended by the CDC, ACOG, and other major health authorities for anyone pregnant or trying to conceive. Methylated folate may help raise folate levels, particularly in individuals with MTHFR gene variants, its effectiveness in NTD prevention has not been clinically validated. Because these birth defects can develop very early in pregnancy, board-certified Obstetrician-Gynecologist, Dr. Natalie Crawford, recommends that if your prenatal contains only methylated folate, you add at least 400 mcg of folic acid daily to ensure adequate protection. If you have a known MTHFR variant or other concerns, please consult your healthcare provider.
It’s recommended that this Protocol be part of a holistic approach to health that includes a nutritious diet, regular exercise, stress management, and regular health screenings. Always consult with a healthcare provider before beginning any new supplement regimen to ensure it is suitable for your health status and needs.
- Veronese, N., Demurtas, J., Pesolillo, G., Celotto, S., Barnini, T., Calusi, G., Caruso, M., Notarnicola, M., Reddavide, R., Stubbs, B., Solmi, M., Maggi, S., Vaona, A., Firth, J., Smith, L., Koyanagi, A., Dominguez, L., & Barbagallo, M. (2020). Magnesium and health outcomes: an umbrella review of systematic reviews and meta-analyses of observational and intervention studies. European Journal of Nutrition, 59, 263-272. https://doi.org/10.1007/s00394-019-01905-w
- Saldeen, P., & Saldeen, T. (2004). Women and Omega-3 Fatty Acids. Obstetrical & Gynecological Survey, 59, 722-730. https://doi.org/10.1097/01.ogx.0000140038.70473.96
- Low, M., Speedy, J., Styles, C., De-Regil, L., & Pasricha, S. (2016). Daily iron supplementation for improving anaemia, iron status and health in menstruating women.. The Cochrane database of systematic reviews, 4, CD009747 . https://doi.org/10.1002/14651858.CD009747.pub2
- Ulrich, C., & Potter, J. (2006). Folate Supplementation: Too Much of a Good Thing?. Cancer Epidemiology Biomarkers & Prevention, 15, 189 - 193. https://doi.org/10.1158/1055-9965.EPI-06-0054
- Prentice, R., Pettinger, M., Jackson, R., Wactawski‐Wende, J., LaCroix, A., Anderson, G., Chlebowski, R., Manson, J., Horn, L., Vitolins, M., Datta, M., Leblanc, E., Cauley, J., & Rossouw, J. (2012). Health risks and benefits from calcium and vitamin D supplementation: Women's Health Initiative clinical trial and cohort study. Osteoporosis International, 24, 567 - 580. https://doi.org/10.1007/s00198-012-2224-2
- Judkins, T., Archer, D., Kramer, D., & Solch, R. (2020). Probiotics, Nutrition, and the Small Intestine. Current Gastroenterology Reports, 22, 1-8. https://doi.org/10.1007/s11894-019-0740-3
- Ford, T., Downey, L., Simpson, T., McPhee, G., Oliver, C., & Stough, C. (2018). The Effect of a High-Dose Vitamin B Multivitamin Supplement on the Relationship between Brain Metabolism and Blood Biomarkers of Oxidative Stress: A Randomized Control Trial. Nutrients, 10. https://doi.org/10.3390/nu10121860
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