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Essential Health for Men in their 40s

Protocol overview

Compare your current stack nutrients to the outlined protocol recommendations.

This Essential Health protocol for Men in their 40s is tailored to address the unique nutritional needs during this decade of life, focusing on supporting hormonal health, energy metabolism, and longevity. It provides a selection of nutrients that contribute to maintaining a healthy body and optimizing overall well-being.

The protocol includes Vitamin D3, Omega-3 Fatty Acids, Magnesium Glycinate, Probiotics, Zinc, Nicotinamide Mononucleotide (NMN), and Ashwagandha. Each component is selected to support different facets of health that are pertinent to men in their 40s, including maintaining healthy hormone levels, supporting energy production at the cellular level, and promoting a balanced response to physical stress.

Last updated: Feb 1, 2024


7 Nutrients

MG

Magnesium Glycinate

200mg

Estimates of magnesium deficiency in the US population vary from 50-75%. Magnesium glycinate is a form of magnesium that is well-tolerated and supports a wide range of biochemical reactions in the body, including those related to energy production and muscle function. [1]

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Ω3

Omega-3 fatty acids

1000mg

Make sure you are taking a product with at least 500 mg combined EPA and DHA, which are essential for cardiovascular health and managing inflammation levels within the body. [2]

D3

Vitamin D3

50mcg

Vitamin D3 supports a variety of bodily functions, including playing a role in the maintenance of normal muscle function and overall hormonal balance. [3]

Pr

Probiotics

1 serving

Probiotics contain bacteria that are beneficial for gut health, which is linked to immune function and can influence overall inflammation. Dosage varies by product (select products with at least 1 billion CFUs and multiple bacterial strains) [4]

Cr

Creatine

5g

Creatine is one of the most widely studied nutrients. It's widely known for enhancing muscular strength, power output and recovery, but has also emerged as a critical nutrient for brain health. Multiple studies have shown creatine supports cognitive function and protects against mental fatigue through improved ATP availability in neurons. [5]

As

Ashwagandha

300mg

Ashwagandha is an adaptogenic herb that helps the body manage stress, supports healthy testosterone levels, and promotes overall vitality. [6]

NM

Nicotinamide Mononucleotide

250mg

Nicotinamide Mononucleotide (NMN) is a precursor to nicotinamide adenine dinucleotide (NAD+), which is essential for energy metabolism and is associated with longevity and the aging process. [7]


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Products

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Recommended for Magnesium Glycinate.
Servings
120.0
Price/serv
$0.28
From
$33.75
Format
tablet
Recommended for Omega-3 fatty acids.
Servings
45.0
Price/serv
$0.72
From
$32.49
Format
capsule
Recommended for Vitamin D3.
Servings
60.0
Price/serv
$0.27
From
$16.00
Format
capsule
Recommended for Probiotics.
Servings
60.0
Price/serv
$0.70
From
$41.80
Format
capsule
Recommended for Creatine.
Servings
90.0
Price/serv
$0.44
From
$39.95
Format
scoop
Recommended for Ashwagandha.
Servings
60.0
Price/serv
$0.42
From
$25.00
Format
capsule
Recommended for Nicotinamide Mononucleotide.
Servings
120.0
Price/serv
$0.57
From
$68.95
Format
tablet

Warnings

Do Not Take With.: Blood-thinning medications or other supplements without consulting a healthcare provider, particularly due to potential interactions with Omega-3 fatty acids.

Do Not Take If: You have any specific health conditions or are taking medication without consulting a healthcare provider, especially considering the effects of NMN and Ashwagandha on metabolism and hormones.

To maximize the benefits of this protocol, a healthy lifestyle is recommended, including a balanced diet, regular exercise, stress management, and sufficient sleep. It’s important to consult with a healthcare provider before starting any new supplement regimen to ensure it is suitable for your health status and to avoid potential interactions with medications.


  1. Baaij, J., Hoenderop, J., & Bindels, R. (2015). Magnesium in man: implications for health and disease.. Physiological reviews, 95 1, 1-46 . https://doi.org/10.1152/physrev.00012.2014
  2. Siscovick, D., Barringer, T., Fretts, A., Wu, J., Lichtenstein, A., Costello, R., Kris-Etherton, P., Jacobson, T., Engler, M., Alger, H., Appel, L., & Mozaffarian, D. (2017). Omega-3 Polyunsaturated Fatty Acid (Fish Oil) Supplementation and the Prevention of Clinical Cardiovascular Disease: A Science Advisory From the American Heart Association. Circulation, 135, e867–e884. https://doi.org/10.1161/CIR.0000000000000482
  3. Antoniak, A., & Greig, C. (2017). The effect of combined resistance exercise training and vitamin D3 supplementation on musculoskeletal health and function in older adults: a systematic review and meta-analysis. BMJ Open, 7. https://doi.org/10.1136/bmjopen-2016-014619
  4. Bermúdez-Brito, M., Plaza-Díaz, J., Muñoz-Quezada, S., Gómez-Llorente, C., & Gil, Á. (2012). Probiotic Mechanisms of Action. Annals of Nutrition and Metabolism, 61, 160 - 174. https://doi.org/10.1159/000342079
  5. Rae, C., Digney, A. L., McEwan, S. R., & Bates, T. C. (2003). Oral creatine monohydrate supplementation improves brain performance: a double–blind, placebo–controlled, cross–over trial. Proceedings of the Royal Society of London. Series B: Biological Sciences, 270(1529), 2147–2150. https://doi.org/10.1098/rspb.2003.2492
  6. Akhgarjand, C., Asoudeh, F., Bagheri, A., Kalantar, Z., Vahabi, Z., Shab-Bidar, S., Rezvani, H., & Djafarian, K. (2022). Does Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta‐analysis of randomized controlled trials. Phytotherapy Research, 36, 4115 - 4124. https://doi.org/10.1002/ptr.7598
  7. Kim, M., Seol, J., Sato, T., Fukamizu, Y., Sakurai, T., & Okura, T. (2022). Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients, 14. https://doi.org/10.3390/nu14040755

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